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In brief, NRF2 detaches from Kelch-like ECH-associated protein 1 and translocates to the nucleus, where it activates the expression of downstream target genes containing antioxidant responsive elements

(See main article on killer yeast.) This can cause problems for winemaking but could potentially also be used to advantage by using killer toxin-producing strains to make the wine

In other words, 5 out of 13 candidates formed G4 structures, accounting for 38% of all candidate aptamers

Hepatobiliary Pancreat Dis Int 20(6):551560 Chuffa LG, Fioruci-Fontanelli BA, Mendes LO, Ferreira Seiva FR, Martinez M, Fvaro WJ, Domeniconi RF, Pinheiro PF et al (2015) Melatonin attenuates the TLR4-mediated inflammatory response through MyD88-and TRIF-dependent signaling pathways in an in vivo model of ovarian cancer