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163 Specifically, Dux, known for enhancing pluripotency during the transition from embryonic stem cells to 2-cell-like ESCs, induces H3K18la through a metabolic switch and p300 recruitment, boosting gene activation for pluripotency and epithelial cells and ultimately accelerating reprogramming efficiency

Affected dogs may experience ongoing symptoms such as diarrhea, vomiting, weight loss, and reduced quality of life, often requiring long-term management

In the control group a lower content of particular elements was observed as compared to tissues undergoing the neoplastic process

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At visit 5, when returning the diaries, the canister was also returned for weighing to check compliance, and the other half of the study product was provided in a new canister for the remainder of the study