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Though abiotic stresses such as drought, salinity, heat, cold light, wounding and senescence can modulate MT gene expression in plants (references cited in Sekhar et al., 2011), among metals, Cu, Cd, Pb, and Zn can strongly induce the plant MT gene expression (reviewed by Mehes-Smith et al., 2013)

A recent study showed that trigonelline, a compound from Trigonella foenum-graecum , inhibited the conversion of TMA to TMAO by inhibiting FMO3

Oxidation, deamidation, and aggregation are the primary concerns

Biochem Soc Trans 29, 717722 (2001)

Shaping the Nrf2-ARE-related pathways in Alzheimer's and Parkinson's diseases