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doi:10.1038/s41598-025-04057-6

The desired C2/3-diamino-group may be introduced via a two-step sequence involving an amination of C2-chloro- group with, for example, ammonia and reduction of C3-nitro group (via, e.g., hydrogenation) to give the precursor 16

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The Lakers have still been outscored by 2.8 points per 100 possessions in 805 total minutes with Doni and James together, though that breaks down to minus-4.6 per 100 in 545 minutes with Deandre Ayton also on the floor and plus-0.9 per 100 in 260 minutes with Ayton off the floor

Patients should not attempt to inject themselves unless a healthcare provider has specifically instructed and trained them, and has confirmed that home administration is safe and appropriate