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doi: 10.1002/mc.23789 29 GyoriDLimELGrantFMSpensbergerDRoychoudhuriRShuttleworthSJet al

In the canonical Wnt pathway, extracellular Wnt ligands trigger intracellular signaling events that stabilize -catenin , allowing it to translocate into the nucleus and activate transcriptional programs controlling cell fate and metabolism