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Neuroprotective effect of curcumin in middle cerebral artery occlusion induced focal cerebral ischemia in rats

GPX4 GPX4, also known as phospholipid hydroperoxide glutathione peroxidase (PHGPx), is the fourth member of the selenium-containing GPX family and is capable of removing lipid peroxides that accumulate in cells [65]

Excessive activation of autophagy may lead to renal tubular atrophy and fibrosis in some cases, but it can also exert anti-fibrotic effects by degrading excess collagen (Zhang et al., 2024)