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1 2 Current Opinion in Clinical Nutrition and Metabolic Care

The starting dose of 2.5 mg is maintained for four weeks, followed by 5 mg for four weeks, then 7.5 mg, 10 mg, 12.5 mg, and finally 15 mg

These structures are related to stress and starvation in C

The maintenance frequency approach represents hybrid strategy where initial intensive treatment (daily application for 3-6 months) establishes improvements, then reduces to maintenance schedule (2-3 times weekly or every other day) rather than complete discontinuation

Aus pharmazeutischer und toxikologischer Sicht ist jedoch eine differenzierte Aufklrung notwendig