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Safety evaluations in both rodent and porcine models underscore ChemoSeed clearance mechanisms, which occur without evidence of local inflammation or fibrosis after eight weeks (162, 163)

*Correspondence: Sen Li, [email protected] Wang, [email protected] This article was submitted to Skeletal Physiology, a section of the journal Frontiers in Physiology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers