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Furthermore, this depletive process can be rescued after estrogen supplementation, increasing the number of spines (Luine and Frankfurt, 2013) and spine synapses in CA1 (Woolley and McEwen, 1992)

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Beyond calcium homeostasis, AS-IV also modulates dysfunctions in other ion channels

This is not surprising taking into account the highly flexible nature of IDPs/IDRs, which are best described as a protein clouds, and the fact that the utilized ensemble low-resolution techniques measure signals representing an average of all the states present in the conformational ensemble, and thereby conceal information about individual structures and their specific features

Bull Exp Biol Med 160 , 283285 (2015)