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Similarly, Rao et al (50) found that increased intracellular iron disrupts the neuromelanin-iron complex in neurons, releasing free iron ions that damage neurons and lead to neuromelanin leakage

doi: 10.1038/ismej.2008.108

The interferon gamma response gene set also included multiple antigen presentation genes

References: He L, Feng D, Guo H, Zhou Y, Li Z, Zhang K, Zhang W, Wang S, Wang Z, Hao Q, Zhang C, Gao Y, Gu J, Zhang Y, Li W, Li M

By establishing a temporal framework for liver organoid development, this work facilitates the standardized application of iHLOs across drug screening, toxicology testing, and disease modeling