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(c) transcellular active transport used by nutrients as sugars, amino acids and vitamins that require specific transporters and energy and (d) endocytosis and basolateral exocytosis via vesicles are used by larger peptides and proteins, large bacterial components or even whole bacteria ( in vivo studies assessing human intestinal permeability (oral administration of sugars or other probes later detected in blood or urine) mainly target the paracellular pathway

Identification of so-called poised bonds in a fragment means that a library of analogues can be rapidly elaborated using standard parallel chemistry

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Spleen tyrosine kinase is involved in the CD38 signal transduction pathway in chronic lymphocytic leukemia