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224 Additionally, eicosapentaenoic acid ethyl ester enhances the antioxidant capacity of UC rats by promoting the expression of the SIRT1 protein, thereby activating the Nrf2 pathway and inhibiting the expression of NF-B to regulate downstream inflammatory cytokines

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10.1021/acs.biomac.0c00992 124 KitanoT.ZerwekhJ

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2.6 Serum biochemical and lipid peroxidation assays The blood samples were collected from the heart and kept at 4C for 2 h