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Whereas, hydrophobic small molecules frequently failed on the road toward clinical use, due to variable and complexed problems including bio-availability, and swift clearance, which in turn because of their physicochemical nature

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Membranes were blocked for 13 h in TBS-T [10 mM TrisHCl pH 8.0,150 mM NaCl, 0.05% (v/v) Tween-20] with 615% (w/v) low-fat dried milk and further incubated overnight at 4 C with the appropriate primary antibody

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