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ADT Auto Dock Tools the binding mode for 1j permits the formation of strong hydrophobic interactions within the apolar pocket surrounding the quinolinium N1-atom, consisting of Tyr20, Tyr204, Tyr242, Leu164, Ala198, and Ala247 residues (hydrophobic residues highlighted by red hashed lines, FIG

Exposure to light can damage B12, so store B12 supplements and fortified foods in a dark, cool place, preferably a refrigerator

Vegans and Vegetarians B12 is primarily found in animal products, so those on plant-based diets may not get enough from food alone

It also serves as a cofactor for several enzymes involved in the biosynthesis of collagen, carnitine, and neurotransmitters, as well as in the metabolism of tyrosine and peptide hormones