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33 suggested that dietary flavanols might not only protect Caco-2 cells against an induced oxidative stress and subsequent cellular death by directly scavenging free radicals, but also by preventing caspase-3 activation and by activating cellular the Caco-2 cells own antioxidant defences, e.g

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Ethics declarations Ethics approval and consent to participate The study protocol was conducted according to the guidelines contained within the Declaration of Helsinki and was approved by the ethics committees of Yokohama City University and Kyoto Prefectural University