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Collectively, cytochrome c release and caspase activation driven by iron-induced ROS are the common routes for the activation of intrinsic apoptosis and pyroptosis, while the suppression of short Fas by iron is a common route for the activation of extrinsic apoptosis and necroptosis

This naturally occurring amino acid is named after the ergot mushroom from which it was first purified in 1909

Through the production of both singlet oxygen and nitric oxide, this method improved tumor cell killing [185]

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The uniform placement of Fe and Mn atoms in the structure indicates the generation of Fe and Mn double sites in the three-dimensional matrix