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Metformin (Mt) or combined oral contraceptive pills (COCPs) should be chosen based on symptoms taking into account the biochemical advantages of combination therapy that targets the two main endocrine disorders associated with PCOS (hyperandrogenism and hyperinsulinemia) [15]

The incorporation of Cu-MBGN is one of the possible pathways to develop a composite material with fewer complications related to secondary caries, marginal leakage and premature material degradation, resulting in more durable and effective restorations

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Your provider will ask about exactly where the pain or weakness is, what makes it better or worse, how far you can walk before symptoms start, whether you get relief from leaning forward or sitting, and any history of back surgeries, falls, or progressive symptoms

Kalaras, M.D