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Bioactive peptides enhance enzymatic defence by approximately 30% and improve cognitive or metabolic indices by 1020% [187,188,189], whereas fatty acids, terpenoids, and polyamines generally yield smaller yet consistent improvements of 2030% across redox and inflammatory dimensions [28,163,190]

It remains to be determined if erlotinib or another potent EGFR inhibitor would be clinically effective in the context of pNF, cNF or OPG, and whether or not patient stratification based on high level of EGFR positivity would be a better approach

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