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Cell culture experiments In vitro mouse BMDC assays Generation of BMDCs was performed by isolating bone marrow cells from femurs/tibias of BALB/c mice and cultured in conditioned-complete DCs medium with granulocyte-macrophage colony stimulating factor for 6 days as previously reported 72

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NCBI-Study Clinical trials show dose-dependent weight loss people without diabetes may lose on the order of 15-20% of body weight over ~72 weeks at higher doses, while those with type 2 diabetes generally have somewhat lower, but still substantial, losses

Trends Pharmacol Sci 38:592607 Prentice BM, Hart NJ, Phillips N, Haliyur R, Judd A, Armandala R, Spraggins JM, Lowe CL, Boyd KL, Stein RW, Wright CV, Norris JL, Powers AC, Brissova M, Caprioli RM (2019) Imaging mass spectrometry enables molecular profiling of mouse and human pancreatic tissue

S., Ovcharenko, A., Cornelissen, N