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Data were acquired using an MS3-based TMT method using the following scan parameters: scan sequence began with an MS1 master scan (Orbitrap analysis, resolution 120,000, 4001700 m/z, RF lens 60%, automatic gain control [AGC] target 2E5, maximum injection time 50 ms, centroid mode) with dynamic exclusion enabled (repeat count 1, duration 15 s)

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6 Although ferroptosis plays a vital role in maintaining the survival of normal cells and tissues, it is increasingly recognized that some oncogenic pathways are closely related to ferroptosis, making cancer cells extremely susceptible to ferroptosis

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