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doi: 10.1002/cbic.202100641 16 Braga-NetoMBCostaDVSQueirozDMMMacielFSde OliveiraMSViana-JuniorABet al

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It should be noted that, compared to control, SFN at low dose or 0.5 M concentration, ex vivo, is able to induce expression of the genes in human peripheral blood mononuclear cells (PBMCs) that encode the enzymes Aldo-Keto Reductase Family 1 Member C1 (AKR1C1) and NQO1 that play a role in reducing radical species [142]

The off-cycle period allows the body natural repair mechanisms to operate independently and prevents dependence on exogenous peptide signaling