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Weight loss outcomes in SURPASS-1 were equally impressive, with mean reductions of 7.0 kg, 7.8 kg, and 9.5 kg for the three tirzepatide doses, respectively, compared to 0.7 kg weight loss with placebo

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nitroso-GSH is more effective at preventing platelet aggregation than at vasodilation, it is nevertheless a potent vasodilator with a longer half-life than nitric oxide alone