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International Journal of Molecular Sciences 22(18):9656

Mechanism of Action of Cyclodextrins in Improving Solubility Cyclodextrins have a ring-shaped structure, with a hydrophobic inner cavity and a hydrophilic outer surface

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The relevance here is evidential, not procedural: because delivery and stability vary so much, comparing results across products and studies is genuinely difficult, and that heterogeneity is one reason a clean answer to the title question has been so slow to emerge

Injection Site Reactions: Redness, swelling, or mild pain at the injection site are possible and typically resolve quickly with proper injection techniques