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These models could further be leveraged to investigate if NSC-secreted factors modulate the gut microbiomes metabolic output or vice versa, providing a mechanistic link between the central and peripheral effects observed in our study

Timeline : 4-6 rounds, 2-4 weeks apart

Determinations of the weights of organs from all F 1b adults and five male and five female weanlings from the F 1b and the F 2b litters showed increased organ:body-weight ratios for the liver at 200 and 800 ppm and for the kidney and brain at 800 ppm in adult F 1b females