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Common triggers include a herniated disc, bone spur, or muscle tightness (like piriformis syndrome)

5-HT(6) receptor recruitment of mTOR as a mechanism for perturbed cognition in schizophrenia

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In cultured lymphocytes that were obtained from young individuals, it was revealed that at concentrations of 0.01 ug/mL induced 2.0 +/- 0.8 chromosome aberrations per cell

This long list of potential triggers can seem daunting, but the most common triggers that cause leaky gut are stress, food sensitivities, nutrient deficiencies, a deficiency in digestive enzymes, an imbalance of gut bacteria, and intestinal infections (including SIBO)