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The role of signaling pathways such as the PI3K/AKT/mTOR and MAPK pathways in mediating the effects of iron overload on mitochondrial function has also been explored

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Sims EK, Bundy BN, Stier K, et al

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The presence of mutated or wild-type IDH has become a key element of the current World Health Organization (WHO) 2021 classification system of CNS tumors ( Figure 1 )

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