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(8) Mind-body techniques: Its essential to incorporate mindfulness and stress reduction techniques like meditation, deep breathing, or yoga to balance nervous system activity, reducing stress and overactivation of the sympathetic response

Additionally, mice overexpressing catalase targeted to the mitochondria shoed reduced cardiomyocyte hypertrophy and significantly diminished cardiac fibrosis (167)

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78 mTORC1 participates in protein, glucose and lipid metabolism mainly through phosphorylation and activation of p70S6 kinase 1 (S6K1), while mTORC2, an effector of PI3K, contributes to the activation of Akt

Neutrophils release myeloperoxidase (MPO) and ROS, exacerbating oxidative stress (101), while M1-like macrophages secrete further pro-inflammatory cytokines, establishing a chronic inflammatory niche (102)