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The peptide earned its name from initial observations that its injection could induce slow-wave sleep (delta sleep) in animals, leading to extensive investigation of its potential as a sleep-promoting agent and its broader physiological roles

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This study suggests that haem is a more critical source for mitochondrial iron utilization than non-haem iron-uptake pathways, thereby supporting the stability of Rieske and SDHB as well as mitochondrial respiration

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