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The study involved 411 adult patients with T2DM and was designed as a randomized, double-blind, placebo-controlled trial where patients received varying doses of danuglipron or a placebo

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Future investigation into the role of these cells in Mtb resistance and disease tolerance to maintain tissue homeostasis may reveal insights into TB protection and pathogenesis

Non-canonical ubiquitination and SUMOylation in NDDs In addition to canonical K48-linked ubiquitination that targets proteins for proteasomal degradation, alternative ubiquitin chain architectures and ubiquitin-like modifications play critical roles in neuronal signaling and survival (Fig