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Excessive caffeine or energy drinks: Large amounts of caffeine may raise stress hormones and oxidative stress, reducing the effectiveness of supplementation

Acidosis could also neutralize ROS associated with radiotherapy, inhibit radiation-induced apoptosis, enhance the activity of P-glycoprotein (P-gp), and/or reduce the rate of proliferation of tumor cells (Peppicelli et al., 2017)

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593 This metabolic shift provides the energy and biosynthetic precursors necessary for T-cell proliferation and activation