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These figures come from preclinical and pharmacokinetic literature, not from approved human dosing and note the standard route for this molecule is oral

Hcy can be converted to cystathionine by the enzyme cystathionine beta-synthase (CBS) which requires pyridoxine (B6) as a cofactor

Regulation of prostaglandin synthesis by reduced glutathione in urinary bladder epithelium

To maintain optimal levels, frequent and costly IV treatments are required, which can be impractical for many individuals

Another well-documented dietary supplement in this field is melatonin (MLT), which is mentioned extensively in the context of dry AMD due to its inhibitory effect on ferroptosis in both RPE cells and PR cells