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Annu Rev Cell Dev Biol 30:503533

As an analog of endogenous growth hormone-releasing hormone (GHRH), tesamorelin boasts a metabolism-stimulating activity that has led to its being approved as a treatment for lipodystrophy, or abnormal adipose fat accumulation associated with antiretroviral therapy for HIV.3 But this same activity can help non-HIV individuals shed abdominal fat of their own, while the peptides GHRH properties make it a suitable therapy for people looking to increase their lean mass

( Histamine is metabolized or cleared from the body via two enzymes, histamine methyltransferase (HNMT) and diamine oxidase (DAO)

A 150 l aliquot of the supernatant was collected, kept at 20 C for 30 min, and centrifuged at 12,000 g for 3 min (4 C)

Czerniecki, S