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3.4 Long-term persistence of active Daratumumab in circulation In order to avoid potential side effects of the anti-CD38 therapy on ICI, the infusion of Daratumumab was stopped for 3 weeks prior to the start of the anti-PD1 treatment

The addition of BPC-157 in our compounded formulation helps reduce these side effects

The limited absorption of the nasal cavity restricts the amount of drug being effectively absorbed, making class I drugs (high permeability, high solubility), according to the Biopharmaceutics Drug Disposition Classification System (BDDCS), particularly suitable for nasal delivery (Ugwoke et al., 2001)

[DOI] [PubMed] [Google Scholar] 101.Skubic C, Drakuli , Rozman D

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