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However, no significant testing for biological safety is performed

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If a supplement is taken daily, at gram doses, for months, it deserves the same tracking you would give training load: dose, duration, benefits, side effects, and a clear stop rule

10.1016/S0092-8674(00)80493-6

Recent experiments showed a surge in IL-6, IL-1, and TNF- levels within irradiated mice serum, which is revoked in MyD88-deficient animals