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Therapeutic strategies aimed at restoring microbial homeostasis, reinforcing gut barrier integrity, or modulating innate immune activation such as probiotics, prebiotics, dietary interventions, fecal microbiota transplantation, and TLR-targeted agents hold promise for disease modification

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On GD 18.5, mice were sacrificed by cervical dislocation, and placental weights, number of fetuses, and fetal weights were recorded