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6,7 ASSOCIATED DISEASES AND SEQUELAE Nonalcoholic fatty liver disease is associated with insulin resistance, central adiposity, increased BMI, hypertension, and hyperlipidemia, which collectively are features of metabolic syndrome 2 (Table 2 8 )

Le MT-2 traverse la barriere hematoencephalique a des doses therapeutiques et active les recepteurs MC3R et MC4R exprimes dans l'hypothalamus (noyau paraventriculaire), le locus coeruleus et la moelle sacree