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The degenerative process of intervertebral discs is often accompanied by the overexpression of matrix metalloproteinases (MMP3, MMP13) and inflammatory factors (IL-1, IL-6, IL-8, PEG2, TNF-) (Wang et al., 2020)

p = 0.003, 94% (1202/1272) vs

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And, uh, when the bacteria are killed, uh, in this case in our gut by our immune cells, uh, they release endotoxin into our bloodstream