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The invention further provides compositions comprising these deuterated isotopologues and methods for treating pRb-positive tumor types including HR-positive and HER2-negative breast cancer in combination with additional agents (i.e

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Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, 82 Gumi-ro 173beon-gil, Bundang-gu, Seongnam 13620, Korea Tel: +82-31-787-7035, Fax: +82-31-787-4051, E-mail: [email protected] Copyright 2024 Korean Endocrine Society This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited