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The present results suggest that the potential diagnostic value of o-tyrosine in RA warrants further investigation, ideally focusing on the routinely accessible plasma/serum samples, thereby avoiding the need for more invasive SF aspiration

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Future studies should focus on more molecular studies as well as RCTs with heterogeneous study designs and large samples in order to elucidate the mechanisms of the KD in tumor therapy and to evaluate the application of the KD in the clinical setting