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doi: 10.3389/fncel.2014.00319 7 ChenP-HGaoSWangY-JXuA-DLiY-SWangD

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Camerota L, Ritelli M, Wischmeijer A, Majore S, Cinquina V, Fortugno P, Monetta R, Gigante L, Marfan Syndrome Study Group Tor Vergata University Hospital, Sangiuolo FC, Novelli G, Colombi M, Brancati F

In the earlier phases of protamination, acetylation of histones increases first, which supports enzyme DNA topoisomerase action, suceeded by the replacement of histones having transition proteins (TP1 and TP2)