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In addition, RvE1 demonstrated synergistic effects with statins in several AS models, markedly reducing proinflammatory cytokine levels, inhibiting foam cell formation, and delaying vascular calcification

Oxidants spontaneously released by alveolar macrophages of cigarette smokers can inactivate the active site of alpha 1-antitrypsin, rendering it ineffective as an inhibitor of neutrophil elastase

Targeting Methionine Metabolism or Sensors for Novel Antifungals The key position that methionine metabolism holds, suggests opportunities to develop novel antifungal drugs (summarized in Figure 2)

Wu C, Pan LL, Niu W, Fang X, Liang W, Li J, et al