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In this capacity, they initiate the activation of autoreactive T lymphocytes, thereby contributing to the diseases progression (59)

J Nutr (2009) 139(11):20448

Hypoxia also might stimulate cancer cells to secrete other pro-angiogenic factors such as FGF, PDGF-B, PDGF-C, HGF, EGF, IL-8, IL-6, Ang-2, SDF1a, PDGF-C, CXCL6 and others, as well as their receptors [85,86]