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The risks and benefits of invasive testing and procedures must be reviewed carefully in patients with all forms of EDS because bleeding complications, inadequate response to regional and local anesthesia, and iatrogenic injury are common

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Anticoagulants act as vitamin K antagonists and prevent the synthesis of some clotting factors

However, there can be no guarantee that the estimates contained in such forward-looking statements will be achieved, as such estimates are subject to numerous risks including those set forth in the Risk Factors section of the universal registration document that was filed with the French Autorit des marchs financiers on April 29, 2025, as updated in the Companys 2025 Half-year financial statements, published on September 25, 2025, both available at www.adocia.com

The key is patience and consistency