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Although we cannot rule out that the increased production of ROS in 3D culture conditions may not be observed under hypoxia, it should be noted that hypoxia itself induces ROS production in numerous cell types, including tumor cells [39]

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In monkeys, negative blank absorbance values of 20 individual sera were measured using the anti-GX-G3 bridging ELISA method, and the OD values were statistically analyzed to identify the mean OD of negative blank sera (0.075) and the NCO value (0.090) (Fig

These findings have led to the hypothesis that basal levels of autophagy are required for the pluripotency acquired by CSCs