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This was the first demonstration that a GLP-1R agonist produces cardiovascular benefit independent of glycaemic effects, expanding the research interest in GLP-1R agonism beyond metabolic and weight endpoints

Some copper is released from the liver into the circulation and is distributed through the body to supply copper for copper-dependent enzymes

In these studies, people with diabetes were treated with 5003,000 mg taurine or placebo daily for 216 weeks

GIP is also implicated in nausea attenuation, which may be why GLP-1/GIP dual agonists like tirzepatide have a slightly better GI tolerability profile than pure GLP-1 agonists

It helps reduce inflammation, speeds up the repair of muscles, tendons, and ligaments, and promotes faster recovery from injuries