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Fibrosis leads to tissue scarring that can impair organ function in many chronic diseases, including pulmonary fibrosis, liver cirrhosis, and systemic sclerosis, but also in musculoskeletal diseases, such as RA and, more importantly, OA (86, 87)

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Relation between TLR4/NF-B signaling pathway activation by 27-hydroxycholesterol and 4-hydroxynonenal, and atherosclerotic plaque instability

Having reviewed the available research into MT-1 and MT-2 doses, it is clear that researchers have adopted a cautious approach when working with this peptide