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All mice used in these studies were 8-14 weeks old, and mice of both sexes were used except when specified in figure legends

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Manual annotation based on canonical markers separated cells into non-endothelial compartments, including stromal (SC), osteoblastic (OB), macrophage (Macro), perivascular (Peri), adipogenic (Adipo), and hematopoietic stem and progenitors (HSPC) and endothelial (ECs) compartments (Fig