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The mice were given free access to food and water and housed under an alternating 12 h lightdark cycle in a room with constant temperature (22 1 C) and 50% relative humidity

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Several statins have long half-lives, including atorvastatin (Lipitor )(14 hrs), pravastatin (Provachol )(19 hrs) & rosuvastatin (Crestor )(77 hrs), and clinical studies indicate no additional benefit when taking these statins at night vs other times during the day

Set realistic expectations for when you'll feel results

For researchers interested in tissue repair , muscle protein synthesis , or fat metabolism , understanding this IGF-1 pathway becomes essential for setting realistic expectations and designing effective protocols