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MnO 2 releases O 2 to improve the hypoxic TME and enhance the cytotoxic efficacy of PCN-224 (Cu)-GOD@MnO 2 (Fig

However, despite showing partially confident fold predictions at sequence identities above 20%, none of the predicted structures resembled the coronaviral Y1, thus questioning Y1s conservation among nidoviruses (details on used species are in Supplemental Data 1)