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Moreover, leptin can cross the BBB and bind to receptors in the arcuate nucleus of the hypothalamus, regulating neurotransmitters such as neuropeptide Y (NPY), cocaine-amphetamine regulated transcript (CART), serotonin (5-HT), and neuropeptide U (NPU), thereby in-directly influencing the bone-brain neural network (61)

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Constant pressure leads to the neural scar effect's gradual loss of hippocampus volume

High resolution long-read telomere sequencing reveals dynamic mechanisms in aging and cancer

For example, glutathione-S-tranferase gene polymorphisms confer reduced risk in pancreatic cancer (Jiao et al., 2007)